Modern medicine has worked wonders in improving the quality and longevity of life. The impact of science on medical matters may well accelerate soon, if we use the huge potential of CRISPR. But the news that the twins in China had been modified before the birth of the genes, in the case of a premature experiment with a man shocked the world.
These mutations are likely to have an effect on twin cognitive function
But ethical problems have been made with regard to the use of genome editing, except fears that CRISPR may be abused or even transformed into a new generation. biological weapons.
These ethical issues were confirmed after being reported in January on two genetically-modified girls born in China.
And now the leading scientist expressed fears that genetically modified children could have Twins Lulu and Nana were believed to have had their genes modified before the birth of the Chinese scientific team using the CRISPR editing tool [1
CRISPR: Premature Case of Experiments in People Shocked the World
The goal was to make girls immune from HIV infection, AIDS is a virus.
And new studies show that The same change introduced into the DNA of girls, the removal of a gene called CCR5, may be associated with greater success at school.
Alcino J. Silva, neurobiologist at the University of California
"The simplest interpretation is that These mutations are likely to occur it's impossible to predict the effect on girls' cognition, and "therefore it should not be done."
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The Chinese team, led by He Jianquui of Southern University of Science and Technology in Shenzhen, said that she used CRISPR to remove CCR5 from human embryos, some of which were later used
HIV requires that the CCR5 gene be included into human blood cells.
The CRISPR experiment was widely condemned as irresponsible, and is under investigation in China.
a debate was fueled as to whether the CRISPR technology could once be used to create super-smart people, possibly as part of a biotechnological race between the United States and China.
There is no evidence that He really intended to change the intelligence of the twins. Read more: Hunting for foreigners "only beginning" says leading scientist
CRISPR: The process can treat everything from cancer, illness hearts and even mental illnesses
CRISPR: Twins of Lulu and Nana had their genes modified by the Chinese scientific group
"As far as I know, we have never heard of it," says Miao Zhou, a professor at the Western University of Medical Sciences in California.
Although He never consulted with brain researchers,
He was first shown in 2016 by Zhou and Silva who found that the removal of the gene from mice had considerably improved their memory.
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The team looked at more than 140 different genetic changes to find that made mice more intelligent.
Silva says that through his research, he sometimes interacts with figures in Silicon. Valley and other cities that, in his opinion, have an unhealthy interest in designer babies with better brains.
"I suddenly realized the saints **, they are really serious about this issue," says Silva.
"My reaction was visceral repulsion and sadness."